Analysis the correlation factors of neonatal lenticulostriate vasculopathy
10.3969/j.issn.1006-5725.2015.19.026
- VernacularTitle:新生儿大脑豆纹血管病变的相关因素分析
- Author:
Yingge MI
;
Changbin ZHANG
;
Ning SHANG
;
Haihao SU
;
Jingjing HU
;
Lijun CAI
;
Bo WANG
- Publication Type:Journal Article
- Keywords:
Lenticulostriate vasculopathy;
Congenital cytomegalovirus infection;
Neonatal asphyxia;
Congenital heart disease;
Hypertensive disorder in pregnancy;
Newborn
- From:
The Journal of Practical Medicine
2015;(19):3202-3204
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation factors of neonatal lenticulostriate vasculopathy. Method Four hundred and forty-seven newborns from Guangdong Women and Children Hospital were enrolled in this study. Clinical data of the newborns were obtained . Brain ultrasound studies of lenticulostriate artery were performed on the newborns. The logistic regression was performed for screening the correlation factors of neonatal lenticulostriate vasculopathy (P < 0.05). Results Results of the univariate logistic regression reveal the correlation factors tcontributing to LSV include congenital cytomegalovirus infection、neonatal asphyxia、congenital heart disease (CHD),hypertensive disorder in pregnancy (P < 0.05, respectively). Multivariate logistic regression analysis was performed on these factors. The congenital cytomegalovirus infection, neonatal asphyxia, CHD,hypertensive disorder in pregnancy were significantly associated with LSV (P < 0.05). Conclusion The congenital cytomegalovirus infection,neonatal asphyxia,CHD,hypertensive disorder in pregnancy are the correlation factors of neonatal lenticulostriate vasculopathy. LSV could be a predictive marker for the future development of neuropsychiatric disorders. The brain ultrasound studies of lenticulostriate artery is suggested to be performed on all infants with the correlation factors.