Progress in interleukin 24 gene engineering protein
10.7644/j.issn.1674-9960.2015.10.016
- VernacularTitle:白细胞介素24基因工程蛋白的研究进展
- Author:
Yao ZHANG
;
Qunfeng MA
;
Chi ZHANG
;
Yinan SHI
;
Hong JIANG
- Publication Type:Journal Article
- Keywords:
interleukins;
gene engineering protein;
neoplasms;
cell proliferation;
apoptosis
- From:
Military Medical Sciences
2015;(10):797-801
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin 24 ( IL-24) has a good prospect in tumor therapy because it can specifically inhibit proliferation in a variety of tumor cells in vitro and in vivo and induce apoptosis of tumor cells without affecting normal cells .Gene therapies which use recombinant adenovirus as a vector have some limitations that restrict the clinical application of IL-24. In comparison, protein drugs have tremendous advantages .In this paper, the progress in research on IL-24 gene engineering protein is elaborated .
