Relevance between Gastrointestinal Microbiota and Helicobacter pylori Eradication Therapy
10.3969/j.issn.1008-7125.2015.10.014
- VernacularTitle:胃肠道微生态与幽门螺杆菌根除治疗的相关性
- Author:
Yue GUAN
;
Zhenyu ZHANG
- Publication Type:Journal Article
- Keywords:
Gastrointestinal Tract;
Microbiota;
Helicobacter pylori;
Eradication Therapy
- From:
Chinese Journal of Gastroenterology
2015;(10):632-634
- CountryChina
- Language:Chinese
-
Abstract:
Gastrointestinal microbiota is a huge and complex system that has multiple influential factors. As an exogenous pathogen,Helicobacter pylori(Hp)may interact with gastrointestinal microbiota. It has been revealed that Hp infection led to an increase in Lactobacillus acidophilus in intestinal tract and a decrease in Actinobacteria,Bacteroidetes and Firmacutes in stomach. Proton pump inhibitors and antibiotics,the major components of eradication regimens for Hp infection,may also have an impact on gastrointestinal microbiota. On the other hand,gastrointestinal microbiota interferes with Hp’s attachment into gastric mucosa. Probiotics combined with eradication therapy could benefit the eradication rate of Hp infection and reduce adverse events.
