The role of humoral immunity in liver graft rejection
10.3760/cma.j.issn.1007-8118.2015.08.016
- VernacularTitle:体液免疫在肝脏移植排斥反应中的作用
- Author:
Hongmeng DONG
;
Duoxian ZHANG
;
Xianliang LI
;
Dongdong HAN
;
Qiang HE
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Acute rejection;
Humoral immunity
- From:
Chinese Journal of Hepatobiliary Surgery
2015;21(8):570-573
- CountryChina
- Language:Chinese
-
Abstract:
Acute rejection is one of the serious early postoperative complications after liver transplantation.Many studies have shown that acute rejection was mainly mediated by T cells,while humoral factors were responsible for chronic rejection.However,accumulating evidences have demonstrated that humoral immune factors also played an important role in early acute rejection and usually resulted in severe adverse events.Here we clarify the role of humoral immunity in liver transplant rejection,which may help guide the clinical management of such patients with humoral rejection after liver transplantation.
