Role of autophagy in occurrence and development of acute pancreatitis
10.3760/cma.j.issn.1007-8118.2015.07.019
- VernacularTitle:自噬在急性胰腺炎发生发展中的作用
- Author:
Fengzhi QU
;
Gang WANG
;
Bei SUN
;
Hongchi JIANG
- Publication Type:Journal Article
- Keywords:
Autophagy;
Acute pancreatitis;
Pathogenesis
- From:
Chinese Journal of Hepatobiliary Surgery
2015;21(7):497-499
- CountryChina
- Language:Chinese
-
Abstract:
The onset of acute pancreatitis (AP) is a complex pathophysiological process mediated by multifactors which are not only interdependent but also influencing each other.So far,the specific molecular mechanism remains uncertain.Autophagy widely exists in a variety of vital phenomena in eukaryotes including the growth,development and pathophysiological progression of normal cells.Autophagy plays an important role in the early damage of acinar cells as well as the development of AP.However,the mechanism is still in doubt.Thus,we overviewed the role of autophagy in the occurrence and progression of AP in order to further enrich the understanding on the pathogenesis.
