Variation of organ position and dose for cervical cancer patients treated with helical tomotherapy
10.3760/cma.j.issn.0254-5098.2015.10.007
- VernacularTitle:宫颈癌调强放疗中靶区变化与剂量分析
- Author:
Yitong LI
;
Yadi WANG
;
Fuli ZHANG
;
Weidong XU
;
Bo YAO
;
Diandian CHEN
;
Na LU
- Publication Type:Journal Article
- Keywords:
Cervical cancer;
Tomotherapy;
Interfractional organ motion;
Actual dose
- From:
Chinese Journal of Radiological Medicine and Protection
2015;35(10):751-755
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the interfractional variation and actual dose for cervical cancer patients treated with tomotherapy.Methods Five patients who received tomotherapy were chosen from Aug 2013 to Feb 2014.A megavohage computed tomography (MVCT) scan was performed before treatment and then registered with the planning CT images.Dose distributions were recalculated and targets were contoured on the MVCT images.The differences between the actual radiation and planning were analyzed.Results In the patients received external radiotherapy, the decline in cervix volume and maximum diameter was 68.90％ and 26.91％ , respectively (t =5.21, 8.39, P ＜0.05).Cervix, uterus and CTV movement in left-right, anteroposterior, superoinferior were 1.43,-7.72, 0.02,-0.40,-1.24, -6.51,-0.43,-1.68and-0.22mm.The medianCTV V95％ was 99.40％ (95.96％-100％), and missing volume was 6.94 cm3 (0-32.30 cm3).Conclusions During radiotherapy for cervical cancer patients, the volume, position and doses are different between initial plan and actual radiation.Based on image guided radiation therapy (IGRT), missing targets are limited.
