Clinical observation of Chuanxiongqingnaokeli for treatment of insomnia
10.3760/cma.j.issn.1008-6315.2015.09.015
- VernacularTitle:川芎清脑颗粒治疗失眠症患者效果观察
- Author:
Yanmei LI
;
Hongkai CHEN
- Publication Type:Journal Article
- Keywords:
Insomnia;
Chuanxiongqingnaokeli;
Estazolam;
Pittsburgh sleep quality index
- From:
Clinical Medicine of China
2015;31(9):820-822
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effects of Chuanxiongqingnaokeli for treatment of insomnia.Methods Eighty-two cases of insomnia patients were randomly divided into treatment group (n =42)and control group (n=40) who were treated in the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from January 2012 to July 2013.The treatment group was administrated Chuanxiongqingnaokeli combined with estazolam tablets while control group was administrated estazolam tablets alone.The indicators including sleep time,easy to waking,sleep time,Pittsburgh sleep quality index and hangover on next day were observed before and after treatment.Results The Pittsburgh sleep quality index of both groups were significantly lower after treatment (treatment group:14.92± 2.89 vs.3.35 ± 1.72,t =2.421,P＜0.05;control group:15.20±3.02 vs.5.81±2.31 score,t=2.537,P＜0.05).And the treatment effect of treatment group was better than control group(t =4.478,P＜0.05).Easy to waking time of the treatment group was (1.49± 1.42) times,sleeping time was (5.78± 1.23) h,hangover on next day was 0,all these data were better than that of control group(2.54±1.56) times,(4.09±1.52) h,37.5％;P＜0.05).The total effective rate of treatment group was 90.5％ (38/42),significantly higher than that of control group (72.5％ (29/40);x2 =61.42,P ＜0.05).Conclusion The chuanxiongqingnaokeli has the significant effects for patients with insomnia.It has more improved in easy to waking and maintaining sleep time significantly which accompanied with advantage of relieving hangover on next day induced by sedative hypnotics at the same time.
