Research of microRNAs on alcohol dependence
10.3760/cma.j.issn.1674-6554.2015.07.025
- VernacularTitle:MicroRNA在酒精依赖机制中的作用
- Author:
Feng XIN
;
Liping LIU
;
Jian HU
- Publication Type:Journal Article
- Keywords:
microRNA;
Alcohol dependence;
Alcohol withdrawal
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2015;24(7):662-664
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the microRNA role in the pathogenesis of alcohol dependence.Methods By computer retrieval Medline,mirbase,PubMed,Chinese journal full-text database (CNKI),ten thousand database and VIP database,manual retrieval relevant references.Literature retrieval time limit are built from the library until July 2014.English database to Alcoholism,Alcohol Dependence,Alcohol Abstinence,Alcohol Amnestic Disorder Fetal Alcohol Spectrum Disorders,mirna as keywords retrieval;Chinese database to Alcoholism,Alcohol Dependence,Alcohol Abstinence,Alcohol Amnestic Disorder Fetal Alcohol Spectrum Disorders,microRNA,etc.Retrieved from the database to the related literature in July 2014.Results A total of 26 studies were recruited including 8 Chinese literatures and 18 English literatures.Conclusion Abnormal expression of miRNAs will become the next research direction.MicroRNAs may become new biomarker of alcohol dependence on diagnosis,may also makes the molecular drug targets,or the molecular simulation for new drug research and development,this could be for the treatment of alcohol dependence provides a new means.
