Research progress in radiotherapy for head and neck tumors in parotid gland protection

VernacularTitle:腮腺保护在头颈部肿瘤放疗中的研究进展
Author: Juan LIU ; Daiyuan MA
Publication Type:Journal Article
Keywords: Head and neck neoplasms; Radiotherapy; Parotid gland
From: Journal of International Oncology 2015;42(9):689-692
CountryChina
Language:Chinese
Abstract: Radiotherapy is the main treatment for head and neck cancer,but it will result in adjacent tissue damage,including radioactive xerostomia,the most common complication.The mechanism of radiation-induced parotid damage injury is unclear.Parotid function test include detection of parotid salivary flow and salivary flow rate,parotid SPECT,CT and MRI,etc.How to protect the parotid glands becomes a hot research in recent years.At present,the main methods of protecting the parotid glands includes selecting patterns of radiotherapy,radiotherapy planning optimization,drugs,stem cell transplantation and gene transduction.