Meta-analysis of TACE combined with PMCT in treatment of advanced liver cancer
10.3760/cma.j.issn.1673-4203.2015.10.004
- VernacularTitle:肝动脉化疗栓塞联合微波消融治疗中晚期肝癌的Meta分析
- Author:
Feng QIN
;
Wei LI
;
Shiqiang SHEN
- Publication Type:Journal Article
- Keywords:
Transcatheter arterial chemoembolization;
Microwaves,coagulation;
Liver neoplasms;
Treatment outcome
- From:
International Journal of Surgery
2015;42(10):658-663
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically the efficacy of transcatheter arterial chemoembolization (TACE) conbined with percutaneous microwave coagulation therapy (PMCT) in treatment of advanced liver cancer.Methods A search was performed by retrieving the domestic and foreign literature database,including WanFang Data,VIP,CNKI,PubMed,Cochrane Library,CBM,EMBASE,Medline,between January 2005 and May 2015.These documents were about the analysis of the efficacy of TACE combined with PMCT in treatment of advanced liver cancer,including complete response(CR),partial response(PR),total effective rate,the levels of AFP declining,1,2,and 3 year survival rate and all the trials must be randomized controlled trials.Meta-analyses were conducted using the Cochrane Collaboration's RevMan 5.2 software.Results Fourteen documents were retrieved,including 989 patients,conbined treatment group 470 patients,simple treatment group 519 patients.The results of Mete-analysis shows that the total effective rate of TACE combined with PMCT is higher than TACE alone in treatment of advanced liver cancer.AFP declining ＞ 50％ of TACE combined with PMCT more obvious than TACE alone.1,2,and 3 year survival rate of TACE combincd with PMCT higher than TACE alone.These differences were statistically significant.Conclusion TACE combined with PMCT might be more effective than TACE alone in treatment of advanced liver cancer.
