Application of strategy of sequential invasive-noninvasive mechanical ventilation in COPD patients with weaning difficulty
- VernacularTitle:有创-无创序贯撤机策略在COPD撤机困难患者中的应用
- Author:
Zhongsuo WANG
- Publication Type:Journal Article
- Keywords:
chronic obstructive pulmonary disease;
mechanical ventilation;
invasive mechanical ventilation;
noninvasive ventila-tion;
clinical weaning
- From:
Basic & Clinical Medicine
2015;(2):224-227
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the strategy of sequential invasive-noninvasive mechanical ventilation in chronic ob-structive pulmonary disease ( COPD ) and specially to explore the role of mechanical ventilation in patients with weaning difficulty .Methods Forty-five cases withe weaning difficulty during January 2009 ~December 2013 from Huludao central hospital emergency section guardianship room were recruited .Compare the rate of re-tracheal intu-bation rate and withdrawal machine success rate in two groups ( intervention group , n=21 , control group , n=24 ) . Results In the intervention group after weaning the 24 h pH, PaCO2 was significantly better than that of the control group ( P<0.01 ) ,in the endotracheal intubation intervention group ,48 h re-tracheal intubation rate was 9.5%, less than the control group ( 41.7%) (P<0.05), The relative risk of intervention group was 0.147 (95%CI, 0.028~0.781 ) .Intervention weaning success rate is significantly higher than that of the control group (85.7%vs 50.0%,P<0.05 ) .Conclusions Sequential invasive-noninvasive mechanical ventilation strategy reduces 48 h in-tubation rate and improve the success rate of weaning .
