Progress on the molecular pathways of radiation-induced cognitive impairment
- VernacularTitle:辐射诱导认知障碍分子机制的研究进展
- Author:
Lianying FANG
;
Jinhan WANG
;
Hui ZHAO
- Publication Type:Journal Article
- Keywords:
radiation;
cognitive impairment;
neurogenesis;
neuronal function;
neuroinflammation
- From:
Basic & Clinical Medicine
2015;(2):244-247
- CountryChina
- Language:Chinese
-
Abstract:
Radiation-induced cognitive impairment is hypothesized to occur because of dynamic interactions be -tween multiple cell types, including astrocytes, endothelial cells, microglia, neurons, and oligodendrocytes.Cur-rent researche indicates that radiation-induced changes include the decrease in hippocampus neurogenesis , altera-tions of neuronal functions , particularly synaptic plasticity , as well as the elevation of neuroinflammatory cytokines .
