Retrospective analysis of infants with human cytomegalovirus infection in Huai′an
10.3969/j.issn.1673-4130.2015.21.015
- VernacularTitle:淮安地区婴幼儿人巨细胞病毒感染回顾性分析
- Author:
Fen LI
;
Zhen ZHANG
- Publication Type:Journal Article
- Keywords:
human cytomegalovirus;
fluorescent quantitative-polymerase chain reaction;
diagnosis;
treatment
- From:
International Journal of Laboratory Medicine
2015;(21):3115-3116
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the infection characteristics of human cytomegalovirus(HCMV)in infants of Huai′an area . Methods Clinical data of 72 infants with HCMV infection ,diagnosed from Nov .2013 to Feb .2015 ,were retrospectively analyzed , including HCMV DNA level of urine samples ,detected by using fluorescent quantitative‐polymerase chain reaction (FQ‐PCR) ,and complications and clinical characteristics .Results The positive rate of HCMV DNA was 90 .3% (65/72) .Among all of the infected infants ,60 cases (83 .3% ) were with pneumonia ,34 cases(47 .2% ) were with hepatitis ,14 cases(19 .4% ) were with hematological diseases ,3 cases(4 .2% ) were with neurological diseases ,and 28 cases(38 .9% ) were with two or more than two types of complica‐tions .Conclusion FQ‐PCR might be useful for the detection of HCM V infection .Clinical manifestation of pneumonia ,hepatitis ,he‐matological diseases ,and so on might be common in HCMV infected infants .FQ‐PCR ,used to detect HCMV DNA ,could be helpful for the early diagnosis and treatment of HCM V infection .
