Clinical significance of NGAL in patients with primary hypertension
10.3969/j.issn.1673-4130.2015.21.006
- VernacularTitle:原发性高血压患者 NGAL 表达水平及临床意义分析
- Author:
Hualing GUAN
;
Jian WU
;
Wenying LU
;
Xiao HE
- Publication Type:Journal Article
- Keywords:
neutrophil gelatinase-associated lipocalin;
primary hypertension;
hypertensive nephropathy;
miciro-albumin
- From:
International Journal of Laboratory Medicine
2015;(21):3090-3091
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the serum and urine levels of neutrophil gelatinase‐associated lipocalin(NGAL) in patients with primary hypertension and related clinical significance .Methods A total of 107 patients with primary hypertension and 100 healthy subjects were enrolled ,and detected for serum and urine levels of NGAL and urinary micro‐albumin .Results Serum and u‐rine levels of NGAL in hypertension patients were (1 .98 ± 1 .49) and (1 .29 ± 0 .54)μg/L ,higher than the (0 .69 ± 1 .02) and (0 .55 ± 0 .35)μg/L in healthy subjects(P< 0 .05) .Urinary micro‐albumin level in hypertension patients was also higher than healthy subjects (P<0 .05) .Conclusion Serum and urine levels of NGAL in patients with primary hypertension could be signifi‐cantly increased ,which might be with important clinical significance in diagnosis ,treatment and prognosis of hypertensive nephropa‐thy .
