Correlation between Helicobacter pylori infection and incidence of myocardial infarction and cerebral infarction
10.3969/j.issn.1673-4130.2015.21.012
- VernacularTitle:幽门螺杆菌感染与心肌梗死及脑梗死相关性研究
- Author:
Shuang LIU
;
Li TAN
;
Xiaoguang XIAO
;
Fenghua ZHANG
;
Feng WANG
- Publication Type:Journal Article
- Keywords:
myocardial infarction;
cerebral infarction;
Helicobacter pylori;
homocysteine
- From:
International Journal of Laboratory Medicine
2015;(21):3108-3109
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate correlation between Helicobacter pylori infection and incidence of myocardial infarction and cerebral infarction ,and serum homocysteine(Hcy) level .Methods A total of 72 patients with myocardial infarction ,86 patients with cerebral infarction and 80 healthy subjects were enrolled and detected for Hp‐IgG and serum Hcy by using enzyme‐linked im‐munosorbent assays and enzymatic cycling method .Relationship between Hp infection and serum level of Hcy were analyzed .Results The positive rate of Hp‐IgG and serum Hcy level in patients with myocardial infarction were significantly higher than healthy subjects(P<0 .05) .Among patients with myocardial infarction ,serum level of Hcy in Hp‐IgG positive patients was higher than that in Hp‐IgG negative patients(P<0 .05) .The positive rate of Hp‐IgG between patients with cerebral infarction and healthy subjects was without significant difference(P>0 .05) .Among patients with cerebral infarction ,serum level of Hcy between Hp‐IgG positive patients and Hp‐IgG negative patients were without significant difference(P>0 .05) .But serum Hcy level in patients with cerebral infarction was significantly higher than that in healthy subjects(P<0 .05) .Conclusion Hp infection might promote the occurrence of myocardial infarction by affecting serum level of Hcy .However ,there might be without obvious correlation between Hp infection and the occurrence of cerebral infarction .And there could be no direct association between high serum level of Hcy in patients with cerebral infarction and Hp infection .
