Isolation and purification of an anticancer activity peptide from protein hydrolysate of Mytilus coruscus
- VernacularTitle:贻贝水解物抗肿瘤活性肽的分离纯化
- Author:
Yongfang YANG
;
Haiqiang YAN
;
Guofang DING
;
Fangfang HUANG
- Publication Type:Journal Article
- Keywords:
Mytilus coruscus;
anticancer peptide;
hydrolysis;
prostate cancer
- From:
Journal of China Pharmaceutical University
2011;42(3):272-275
- CountryChina
- Language:Chinese
-
Abstract:
In this studies, an anticancer peptide was isolated from the enzymatic hydrolysate of Mytilus coruscus.CCK-8 assay was used as guide in activity screening through the isolation process of membrane filtration, DEAEsepharose chromatography, Sephadex G-25 exclusive chromatography and RP-HPLC. An anticancer peptide was obtained and identified as Asp-Leu-Tyr.
