Tandem Claisen rearrangement/Diels-Alder reaction in ionic liquid
10.3321/j.issn:1000-5048.2009.06.001
- VernacularTitle:离子液体中的Claisen重排/Diels-Alder加成串联反应研究
- Author:
Xiaorong LIU
;
Qidong YOU
;
Jinxin WANG
- Publication Type:Journal Article
- Keywords:
ionic liquid;
tandem Claisen rearrangement/Diels-Alder reaction;
caged structure
- From:
Journal of China Pharmaceutical University
2009;40(6):481-485
- CountryChina
- Language:Chinese
-
Abstract:
Aim: The tandem Claisen rearrangement/Diels-Alder reaction in ionic liquid was carried out to find better changes for the conversion. Methods: The synthesis started with replaced benzoic acid via acylation, cycli-zation, demethylation, allylation and then tandem Claisen rearrangement/Diels-Alder reaction in trational solvent and ionic liquid separately. Results: BmimBF_4 raised the yield of the target compound and shortened the reaction time compared with the traditional solvent Conclusion: BmimBF_4 can promote the tandem Claisen rearrange-ment/Diels-Alder reaction.
