Research advances in wogonin's anti-tumor effects
10.3321/j.issn:1000-5048.2009.06.021
- VernacularTitle:汉黄芩素抗肿瘤作用的研究进展
- Author:
Li YANG
;
Qidong YOU
;
Yong YANG
;
Qinglong GUO
- Publication Type:Journal Article
- Keywords:
wogonin;
tumor;
apoptosis;
angiogenesis
- From:
Journal of China Pharmaceutical University
2009;40(6):576-579
- CountryChina
- Language:Chinese
-
Abstract:
Latest researches have indicated that wogonin, a naturally occurring flavonoid, could sensitize tumor cells to apoptosis, selectively induce apoptosis in the malignant tumor cells, inhibit tumor angiogenesis, reverse drug resistance as well as promote tumor cell death synergistically with other anti-cancer agents. This paper sum-marizes the involving mechanisms of wogonin's anti-tumor effects.
