Comparative analyses of clinical and pathological characteristics between types 1 and 2 endometrial uterine cancers
10.3760/cma.j.issn.1008-1372.2015.08.002
- VernacularTitle:Ⅰ型和Ⅱ型子宫内膜癌临床病理特点对比分析
- Author:
Xiaomao LI
;
Huixia YE
;
Minjuan YE
;
Jihong LIU
;
Mian HE
- Publication Type:Journal Article
- Keywords:
Endometrial;
neoplasms/PA
- From:
Journal of Chinese Physician
2015;17(8):1124-1126
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and pathological characteristics between types 1 and 2 endometrial uterine cancers.Methods The clinical materials of 9 437 patients with uterine cancer were collected with retrospective analysis from 62 hospitals during 2000 to 2010.Results The mean age of type 1 endometrial cancers was less than type 2.There were more young patients in type 1 endometrial cancers.The mean menopause age of type 2 endometrial cancers was greater than type 1.The mean age of menarche,obesity,diabetes,hypertension,infertility,and nulliparous were not significant differences between types 1 and 2 endometrial cancers.There were more patients with advanced tumor,deep myometrium invasion,estrogen receptor (ERs) negative,progesterone receptor (PR) negative,P53 positive,lymph vascular space involvement,cervical stromal invasion,adnexal metastasis,and lymph node metastasis in type 2 endometrial cancers.Conclusions Type 2 endometrial uterine cancers occurred in elder people with more pathological risk factors and more malignant biological activities.