Neuroimmunomodulatory effects of vitamin D and its relationship with neuropsychiatric disorders
10.3760/cma.j.issn.1674-635X.2015.04.012
- VernacularTitle:维生素D的神经免疫调节作用及其与神经精神疾病的关系
- Author:
Ruili DANG
;
Yujin GUO
;
Yungui ZHU
;
Pei JIANG
- Publication Type:Journal Article
- Keywords:
Vitamin D;
Neuropsychiatric disease;
Immune modulation
- From:
Chinese Journal of Clinical Nutrition
2015;23(4):250-254
- CountryChina
- Language:Chinese
-
Abstract:
Over the last decade,a growing body of evidence has indicated that vitamin D is not only crucial in maintaining calcium-phosphorus homeostasis and bone density,but also implicated in the regulation of immune system and the maintenance of the normal function of central nervous system.A variety of neuropsychiatric disorders such as multiple sclerosis,Alzheimer's disease,Parkinson's disease,schizophrenia,and depression are suggested to be associated with vitamin D deficiency and immune activation.In this review,we summarize the recent key findings concerning the effect of vitamin D on neuroimmmune modulation and its potential role in those neuropsychiatric disorders.
