Diagnosis and treatment for anemia of chronic kidney disease in children
10.3760/cma.j.issn.2095-428X.2015.17.003
- VernacularTitle:小儿慢性肾脏病贫血的诊断与治疗
- Author:
Xiaorong LIU
- Publication Type:Journal Article
- Keywords:
Anemia of chronic kidney disease;
Diagnosis;
Treatment;
Iron;
Erythropoiesis stimulating agent;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;30(17):1289-1293
- CountryChina
- Language:Chinese
-
Abstract:
There are many reasons for children with anemia of chronic kidney disease (CKD), such as chronic renal insufficiency due to lack of raw materies erythropoietin(iron,folic acid, vitamin B12 deficiency), shortening of the life of red blood cells and blood loss, bone marrow suppression by urine toxins such as erythropoietin.But the main reason is decreased production of renal erythropoietin accompanying chronic renal insufficiency.Anemia affects tissue's oxygen supply, utilization, and cardiac output, and patients often show a series of pathophysiology of immune dysfunction,such as fatigue, difficulty in breathing, enlargement of the hearts, ventricular hypertrophy, heart failure, cerebral insufficiency ,cognitive decline ,affecting the prognosis and quality of life of patients.Renal anemia requires aggressive treatment,which is closely related to the survival and quality of life in patients with chronic renal failure.This paper elaborates on the diagnosis of anemia in children with CKD, the evaluation strategies of anemia,iron therapy and erythropoiesis stimulating agents treatment.
