Mechanisms of perineural invasion and its effect on early cervical cancer
10.3760/cma.j.issn.1673-422X.2015.11.020
- VernacularTitle:神经周围浸润的发生机制及对早期宫颈癌的影响
- Author:
Fang XIA
;
Xiuhua XUE
;
Ping ZHANG
- Publication Type:Journal Article
- Keywords:
Neoplasms,nerve tissue;
Neoplasm invasiveness;
Uterine cervical neoplasms
- From:
Journal of International Oncology
2015;42(11):869-872
- CountryChina
- Language:Chinese
-
Abstract:
Mechanisms of perineural invasion may include the effect of microenvironment, the interaction of cancer cell and nerve, the action of stromal cell and cancer cell, signal transduction between the cancer cell and nerve by the involvement of the neurotrophin and its receptor, chemokines and its receptor.Its impacts on early cervical cancer include surgery, adjuvant therapy, prognosis and so on.