Research status of matrix metalloproteinase-9 on metastatic breast cancer
10.3760/cma.j.issn.1673-422X.2015.11.013
- VernacularTitle:基质金属蛋白酶-9在转移性乳腺癌中的研究现状
- Author:
Li LI
;
Weili SUN
;
Delin LIU
;
Yuan WU
;
Youqun WANG
- Publication Type:Journal Article
- Keywords:
Matrix metalloproteinase 9;
Breast neoplasms;
Prognosis;
Reference standards
- From:
Journal of International Oncology
2015;42(11):845-848
- CountryChina
- Language:Chinese
-
Abstract:
Matrix metalloproteinase-9 (MMP-9) can promote the invasion and metastasis of breast cancer through various mechanisms.The expressions of MMP-9 in the patients with breast cancer are correlated with the prognosis.The higher expression of MMP-9 indicates poorer prognosis.It is suggested that the level change of MMP-9 pre and post treatment can be used as a reference standard for judging the prognosis and clinical effect.