Expression and role of miRNA-375 in digestive system tumors
10.3760/cma.j.issn.1673-422X.2015.11.018
- VernacularTitle:miR-375在消化系统肿瘤中的表达及作用
- Author:
Zheng CHEN
;
Xiaofeng LIU
;
Qianqian DONG
;
Shulin MA
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Digestive system neoplasms;
Neoplasm metastasis
- From:
Journal of International Oncology
2015;42(11):863-865
- CountryChina
- Language:Chinese
-
Abstract:
micmRNA (miRNA) plays an important role in biological processes via regulating gene expression in the level of posttranscription.Increasing number of studies reveal that miR-375 is downregulated in digestive system tumors, and is related to tumorigenesis.Overexpression of miR-375 can inhibit growth and metastasis of tumors through repressing the expression of target genes.
