Progress of mitochondrial respiratory chain dysfunction in septic children
10.3760/cma.j.issn.1673-4408.2015.05.014
- VernacularTitle:脓毒症患儿线粒体呼吸链功能障碍的研究进展
- Author:
Ning LI
- Publication Type:Journal Article
- Keywords:
Sepsis;
Mitochondrial respiratory chain
- From:
International Journal of Pediatrics
2015;42(5):534-537
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is a complicated pathophysiological disorder arising from a systemic inflammatory response to infection.Because of high morbidity,high mortality and high cost of treatment, sepsis has caused global attention and become a hot spot in pediatric intensive medical research.Increasing number of studies have shown a close correlation between the occurrence of multiple organ dysfunction syndrome and mitochondrial dysfunction in sepsis.A major feature in sepsis is dysfunction of mitochondrial oxidative phosphorylation.This review discusses the dysfunction of mitochondrial respiratory chain in sepsis.
