von Willebrand factor, factor Ⅷ and acute ischemic stroke

VernacularTitle:von Willebrand因子、因子Ⅷ与急性缺血性卒中
Author: Xinyue CHEN ; Shuang LI ; Guorong BI
Publication Type:Journal Article
Keywords: Stroke; Brain Ischemia; von Willebrand Factor; Factor Ⅷ
From: International Journal of Cerebrovascular Diseases 2015;23(7):537-541
CountryChina
Language:Chinese
Abstract: von Willebrand factor (vWF) and factor Ⅷ (FⅧ) exist in a complex form in blood.After being activated,they mediated platelet adhesion and aggregation,and play an important role in the course of thrombosis.The levels in blood of both of them were affected by a variety of factors.vWF and FⅧ are closely associated with the risk,etiological type,severity and outcome of acute ischemic stroke.Studies on the corresponding antagonistic drugs have made a breakthrough,and these drugs may become more advantageous antithrombotic s.