Progress of a disintegrin and metalloproteinase 10 in urinary tract diseases
10.3760/cma.j.issn.1673-4408.2015.05.002
- VernacularTitle:去整合素金属蛋白酶10在泌尿系统疾病中的研究进展
- Author:
Ling HOU
- Publication Type:Journal Article
- Keywords:
A disintegrin and metalloproteinase 10;
Urinary tract
- From:
International Journal of Pediatrics
2015;42(5):488-491
- CountryChina
- Language:Chinese
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Abstract:
A disintegrin and metalloproteinase 10 is a zinc dependent transmembrane type Ⅰ multi-domain of protein which is highly conserved in evolution and mediates protein maturation and ectodomain shedding, with protein hydrolysis, cellular adhesion, cellular fusion and signal transmission.This article reviews its structure and function, the substrate and relative signaling pathways, the factors influencing its expression and catalytic activity,the research progress in urinary tract diseases.
