Survival analysis of patients with non-Hodgkin lymphoma in Qidong from 1972 to 2011
10.3760/cma.j.issn.1009-9921.2015.10.010
- VernacularTitle:启东市1972年至2011年非霍奇金淋巴瘤患者生存率分析
- Author:
Jian ZHU
;
Jianguo CHEN
;
Yonghui ZHANG
;
Yongsheng CHEN
;
Lulu DING
- Publication Type:Journal Article
- Keywords:
Lymphoma,non-Hodgkin;
Survival;
Epidemiology
- From:
Journal of Leukemia & Lymphoma
2015;24(10):608-612
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the survival rates of patients with non-Hodgkin lymphoma (NHL) in Qidong from 1972 to 2011,in order to provide the basis for the prognosis assessment and the control of this cancer.Methods A total of 1 472 registered NHL cases were followed up to April 30, 2012.Cumulative observed survival (OS) rate and relative survival (RS) rate were calculated using Hakulinen method performed by the SURV 3.01 software developed at the Finnish Cancer Registry.Results The 1-, 3-, 5-, 10-, 20-and 30-year OS rates were 32.48 ％, 19.30 ％, 15.78 ％, 12.76 ％, 9.54 ％ and 7.63 ％, and the RS rates were 33.49 ％, 21.18 ％, 18.46 ％, 17.79 ％, 19.37 ％ and 22.44 ％, respectively.The 1-, 3-, 5-, 10-, 20-and 30-year RS rates of males vs females had no statistically significant differences (x2 =3.32, P =0.767).The 5-year RS rates of age groups 0-14, 15-34, 35-44, 45-54, 55-64, 65-74, and ≥75 were 22.99 ％, 20.51％,18.42 ％, 20.96 ％, 18.72 ％, 17.32 ％, 10.60 ％, and the 10-year RS rates were 23.04 ％, 15.55 ％, 15.91％,16.36 ％, 18.59 ％, 19.70 ％, 20.93 ％, respectively.The age group 0-14 had the highest 5-and 10-year RS rates.Remarkable improvement could be seen in the 5-year RS rate from 7.76 ％ in 1973-1977 to 26.79 ％ in 2003-2007, and the 10-year OS rate from 6.63 ％ in 1973-1977 to 15.52 ％ in 1998-2002, respectively.Conclusions The outcome of NHL in Qidong has been improved gradually from 1972 to 2011, but the gaps of survival rates in NHL patients between China and the developed countries still exist.Research on the diagnosis and treatment of NHL should be further emphasized.
