Research progress of targeted agents in the treatment of mantle cell lymphoma
10.3760/cma.j.issn.1009-9921.2015.10.019
- VernacularTitle:靶向药物治疗套细胞淋巴瘤的研究进展
- Author:
Zhiqiang ZHAO
- Publication Type:Journal Article
- Keywords:
Lymphoma,mantle cell;
Target agent
- From:
Journal of Leukemia & Lymphoma
2015;24(10):632-635
- CountryChina
- Language:Chinese
-
Abstract:
Mantle cell lymphoma (MCL) is a rare subtype of non-Hodgkin lymphoma.The MCL is classified into two subtypes, some patients have a chronic/indolent course and the others have a more aggressive course and short survival.In recent years, some novel therapeutic target agents for MCL have reports.These target agents achieve efficacy comparable to conventional chemotherapy in relapsed/refractory MCL.Therapeutic targents for MCL include the surface antigens of B-cell lymphoma, B-cell receptor signaling, DNA damage response pathway and the cellular microenviroment.This review focused on the recent research progress of target agents in the treatment of MCL.
