The risk analysis of acute renal insufficiency in perioperative of non-small cell lung cancer

VernacularTitle:非小细胞肺癌术后并发急性肾功能不全的危险因素分析
Author: Xin LI ; Yixin CAI ; Ni ZHANG ; Xiangning FU
Publication Type:Journal Article
Keywords: Non-small cell lung cancer; Acute renal insufficiency; Risk factors
From: Chinese Journal of Thoracic and Cardiovascular Surgery 2015;31(9):549-552
CountryChina
Language:Chinese
Abstract: Objective To discover the risk factors of acute renal insufficiency(ARI) in perioperative of non-small cell lung cancer(NSCLC).Methods We took a retrospective study to analysis and summarize the clinical features of 33 ARI cases and 721 controls,all subjects were histopathologically confirmed NSCLC from January 2007 to October 2013.Logistic regression analysis was conducted to analyze the association between the risk factors and ARI.Results There were significant differences between the two groups in operation age,level of preoperative creatinine,preoperative rehydration and the use of plasma substitutes.After adjustment by confounding factors,operation age older than 60 years old and the use of plasma substitutes had higher risk of ARI [adjusted OR was 2.93 (1.30-6.62),95 ％ CI was 6.04 (1.41-25.87),respectively].Preoperative rehydration was protective factor of ARI(adjusted OR was 0.37,95％ CI was 0.17-0.83).Conclusion Operation age (≥ 60 years old) and the use of blood substitutes are independent risk factors of ARI,while preoperative rehydration can reduce the incidence of ARI after surgery.