The study on treatment efficacy using Gemstone spectral CT in patients with lung cancer after radiofrequency ablation
10.3760/cma.j.issn.1001-4497.2015.08.010
- VernacularTitle:宝石能谱CT在肺癌射频消融术中的应用
- Author:
Lei LIU
;
Yi ZHANG
;
Xiuyi ZHI
;
Baodong LIU
- Publication Type:Journal Article
- Keywords:
Lung carcinoma;
Radiofrequency ablation;
Gemstone spectral computed tomography(CT)
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2015;31(8):490-493
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic effects afer radiofrequency ablation(RFA) in 24 patients with pulmonary neoplasms through quantitative iodine-based and water-based material decomposition images with spectral computed tomography(CT) imaging.Methods 30 patients(19 male,11 female;age range,52-85 years;mean age,69 years;26 peripheral lung cancer,4 central lung cancer) underwent lung radiofrequency ablation on a GE Discovery CT750HD scanner from March 2012 to March 2013.We compared the volume,CT value,water-based value and iodine-based value of lung tumor before and after the RFA using spectral imaging mode.Results 22 of 30 tumors was bigger after the RFA,8 had no change.Through water-based material decomposition images,the water content in the tumors were increased from(1 014.76 ±6.83) mg/ml to (1 022.71 ± 10.16)mg/ml after RFA,and the difference was significant (t =-2.329,P ＜ 0.05).The iodine-based value in parenchyma of the tumor was 2.49 ± 0.74 mg/mL before the RFA.The tumor was most or completly necrosis after the RFA,the value of iodine in the area of necrosis was (0.45 ± 0.29) mg/mL,which was obviously reduced than before (t =11.072,P =0.000).Conclusion Through compared with the volume,CT value,water-based value and iodine-based value of the parenchyma of the tumors before and after the RFA with spectral computed tomography(CT) imaging,we can know the morphology and metabolism of the tumors to investigate the short term results.
