The curative effect of transcranial magnetic stimulation combined with hyperbaric oxygen after cerebral infarction
10.3760/cma.j.issn.0254-1424.2015.07.011
- VernacularTitle:经颅磁刺激联合高压氧治疗脑梗死的疗效观察
- Author:
Lijun XIONG
;
Mei ZHANG
;
Wuping XU
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Hyperbaric oxygen;
Transcranial magnetic stimulation;
Neurological function improvement;
Stroke
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2015;37(7):522-526
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effectiveness of transcranial magnetic stimulation (TMS) combined with hyperbaric oxygen (HBO) in treating cerebral infarction.Methods Totally 120 patients with cerebral infarction were randomly divided into a control group,a treatment group A and a treatment group B,40 cases in each group.The control group was given conventional treatment,the treatment group A was treated by HBO on the basis of conventional therapy,and the treatment group B was treated by HBO combined with TMS,10 d for a period of treatment.Before and after 2 courses of treatment,all patients' neurological defect was evaluated using National Institutes of Health Stroke Scale (NIHSS).Their central motor conduction time (CMCT) and the expression of brain derived neurotrophic factor (BDNF) and nerve growth factor (NGF) were also assessed.Results After treatment,the average NIHSS score and effective rate of the treatment group B was (7.35 ± 1.98) and 92.5％ respectively,significantly better than the other two groups.Moreover,the average BDNF content [(4.96 ± 1.20) ng/ml] and NGF content [(152.36 ± 18.01)pg/ml] of the treatment group B after treatment were significantly better than before treatment,and those of the other two groups after treatment.Conclusion TMS combined with HBO is effective in treating cerebral infarction.This may relate to its strengthening the expression of neurotropic factors.
