Clinical characteristics and prognosis analysis of 50 patients with primary Waldeyer's ring non-Hodgkin lymphoma
10.3760/cma.j.issn.1009-9921.2015.09.009
- VernacularTitle:原发韦氏环非霍奇金淋巴瘤50例临床特征和预后分析
- Author:
Deliang LIU
;
Weimin DONG
;
Feng YAN
;
Weiying GU
- Publication Type:Journal Article
- Keywords:
Lymphoma,non-Hodgkin's;
Waldeyer's ring;
Prognosis
- From:
Journal of Leukemia & Lymphoma
2015;24(9):548-550
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinicopathological characteristics and prognosis of primary Waldeyer's ring non-Hodgkin lymphoma.Methods From Jan 2008 to Dcc 2013, 50 patients with primary Waldeyer's ring non-Hodgkin lymphoma were retrospectively analyzed.Kaplan-Meier method was used for survival analysis.Log-rank method was used for univariate analysis.Results Waldeyer's ring diffuse large B-cell lymphoma (DLBCL) and extranodal nasal-type NK/T-cell lymphoma (ENKTCL) were the common pathological types of primary Waldeyer's ring non-Hodgkin lymphoma accounting for 56 ％ (28/50) DLBCL and 34 ％ (17/50) ENKTCL, respectively.The age at onset of ENKTCL patients was younger than that of DLBCL patients.Two groups had different primary sites, including 50.0 ％ (14/28) of DLBCL with tonsillar disease and 88.2 ％ (15/17) of ENKTCL with nasopharynx disease.The short phase effect of DLBCL group was higher than that of ENKTCL group.The overall survival (OS) and progression-free survival (PFS) rates had significant differences between DLBCL and ENKTCL (x2 =4.45, P =0.035;x2=6.47, P =0.011).Conclusion DLBCL and ENKTCL are different in clinical characteristics.The short phase effect and prognosis of DLBCL are obviously better than those of the ENKTCL.
