Advances in pathogenesis and treatment of myeloproliferative neoplasms
10.3760/cma.j.issn.1009-9921.2015.07.007
- VernacularTitle:骨髓增殖性肿瘤治疗与发病机制的研究进展
- Author:
Dayong HUANG
;
Zhao WANG
- Publication Type:Journal Article
- Keywords:
Myeloproliferative neoplasms;
JAK2 gene;
Gene mutation;
Therapy
- From:
Journal of Leukemia & Lymphoma
2015;24(7):408-411
- CountryChina
- Language:Chinese
-
Abstract:
As originated from hematopoietic stem cell clonal diseases,bcr-abl-negative chronic myeloproliferative neoplasms (MPN) include polycythemia vera (PV),essential thrombocythemia (ET) and primary myelofibrosis (PMF).With the discovery of JAK2 mutations,many new mutations have been identified.With the in-depth study of gene mutation,the pathogenesis of MPN has been gradually uncovered.Novel drugs have been developed accordingly.
