The prospective randomized controlled study of primary pterygium surgery
10.3760/cma.j.issn.1008-6706.2015.22.011
- VernacularTitle:手术治疗原发性翼状胬肉的前瞻性随机对照研究
- Author:
Feng HUA
;
Zhengyi LI
;
Jimeng CHEN
;
Guoting HOU
- Publication Type:Journal Article
- Keywords:
Pterygium;
Limbal stem cell;
Transplantation;
Mitomycin C
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(22):3392-3394
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study two different methods in treatment of primary pterygium surgery on corneal epithelial wound repair and the influence on the recurrence rate.Methods Used prospective controlled study,accord-ing to a number table 128 patients with 128 eyes were randomly divided into control group (64 cases),and observa-tion group (64 cases).The two groups of patients underwent pterygium excision and limbal stem cell transplantation. The observation group (64 eyes)received 0.2 mg/mL mitomycin C of mitomycin -C(MMC)adjuvant therapy. Corneal epithelial wound repair speed was observed.The patients were followed up for 6 -12 months,average 8.5months,the recurrence rate of pterygium was observed in the two groups.Results The grafts were smooth,and the conjunctival flap healed well in the two groups.The postoperative corneal epithelial healing time of the control group and the observation group were (2.13 ±0.37)d,(2.87 ±0.41)d,there was statistically significant difference (t =4.91,P <0.01);The postoperative recurrence rates were 6.25%,4.69% respectively,there was no statistically sig-nificant difference (χ2 =0.48,P >0.05).Conclusion There was no difference in recurrence rate between two kinds of pterygium surgical method,but the combined MMC can cause corneal epithelial healing delay.
