Multicenter survey on the prevalence and risk factors of metabolic syndrome among patients with maintenance hemodialysis
10.3969/j.issn.1006-5725.2015.18.045
- VernacularTitle:维持性血液透析患者代谢综合征患病现状及危险因素的多中心调查
- Author:
Junbao ZHANG
;
Xiaozhou HU
;
Yan ZHANG
;
Shaoting WANG
- Publication Type:Journal Article
- Keywords:
Maintenance hemodialysis;
Metabolic syndrome;
Prevalence;
Risk factors
- From:
The Journal of Practical Medicine
2015;(18):3075-3078
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence of metabolic syndrome in patients with maintenance hemodialysis, and to analyze the potential risk factors. Methods The clinical data of 472 patients with maintenance hemodialysis from 7 blood purification centers were collected. Patients were divided into the MS group and the non-MS group. The demographic data , anthropometric examinations , dialysis prescription and results of laboratory were compared between these two groups. Multivariate Logistic regression analysis was performed to analyze the risk factors of MS. Results The morbidity of MS was 34.75%. There were significant differences in weight , waist circumference , waist-hip ratio , frequency of dialysis , time of hemodialysis perweek , urea reduction ratio, urea clearance index (Kt/v), iron, intact parathyroid hormone (iPTH), leukocytes, high sensitivity C-reactive protein (hs-CRP) between these two groups (P < 0.05, resectively). Multivariate Logistic regression analysis revealed that iron (OR = 1.084, P = 0.042), iPTH (OR = 1.754, P = 0.035), waist-hip 1ratio (OR = 2.013,P = 0.021), hs-CRP (OR = 4.245,P = 0.000)were correlated with MS. Conclusion The morbidity of MS in patients with maintenance hemodialysis is higher. Iron, iPTH, waist-hip ratio, hs-CRP are potential risk fctors of MS for the patients with maintenance hemodialysis.
