Effects of CRRT at early stage in patients with hyperlipoidemia severe acute pancreatitis
10.3760/cma.j.issn.1008-6706.2015.23.010
- VernacularTitle:早期连续性肾替代治疗高脂血症性重症急性胰腺炎的临床观察
- Author:
Xiandan WU
;
Jinbo ZHANG
;
Guobin XU
;
Meiping DONG
;
Jinqiang ZHU
;
Laichao YAN
;
Liexiang CAO
- Publication Type:Journal Article
- Keywords:
Pancreatitis;
Hyperlipoidemia;
Renal replacement therapy(CRRT)
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(23):3552-3554
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of early continuous renal replacement thempy(CRRT)for hyperlipoidemia severe acute pancreatitis (HLSAP)patients.Methods 32 HLSAP patients were randomly divided into control group and CRRT treatment group.The levels of serum triglyceride(TG),serum and urine amylase,the APACHEⅡscore,the incidence of mechanical ventilation were compared between the two groups.Results The levels of serum TG was significantly lower in CRRT group than that in the control group in day 3(t =2.885,P =0.003). The APACHE II score,incidence rate of mechanical ventilation,the fatality rate were significantly lower in CRRT group than those in the control group in day 3(χ2 =4.572,t =4.912,χ2 =4.043;P =0.032,0.027,0.044).There were no significant differences between late group than that early group in age,gender,APACHE II score(all P >0.05).There were no significant differences between the two groups in the levels of amylase in serum and urine in day 3(all P >0.05).Conclusion Early CRRT therapy can eliminate the level of TG in HLSAP patients,may improve the prognosis of HLSAP patients.