Progress of phage display technology in cancer
10.3760/cma.j.issn.1673-422X.2015.10.011
- VernacularTitle:噬菌体展示技术在肿瘤研究中的应用
- Author:
Junqian LUO
;
Suming DONG
;
Fan ZHANG
;
Xiaofeng YANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Phage display technology
- From:
Journal of International Oncology
2015;(10):759-761
- CountryChina
- Language:Chinese
-
Abstract:
Phage display technology describes a genetic engineering technique in which a library of peptide or protein variants is expressed on the outside of a phage virion,while the genetic material encodes each variant resides on the inside and maintains the relatively independent spatial structure and biological activity. Studies have shown that the phage display technology can be used to screen tumor homing peptides,target trans-porting anti-substances,develop vaccines,research diagnostic regents and image in blood vessels.Thus phage display technology is a powerful method to overcome the challenge of tumor disease.
