Anti-hepatoma mechanisms of ginsenoside
10.3760/cma.j.issn.1673-422X.2015.10.019
- VernacularTitle:人参皂苷的抗肝癌作用机制
- Author:
Na ZHANG
;
Yinglu FENG
- Publication Type:Journal Article
- Keywords:
Ginsenosides;
Liver neoplasms;
Pharmacology
- From:
Journal of International Oncology
2015;(10):786-788
- CountryChina
- Language:Chinese
-
Abstract:
Ginsenosides (GS)as the main ingredient of ginseng,include dozens of monomer,such as Rg3,Rh2,Rd,Rh1 ,Rg2,etc.GS and various monomers have different anti-hepatoma mechanisms.The main mechanism includes the following aspects,inducing the apoptosis of liver cancer cells,inhibiting the prolifera-tion,invasion and metastasis,reversing the multidrug resistance of liver cancer cells,increasing therapeutic effects by combining with other treatments,improving the immune function of organism and inhibiting hepatic glu-cose production.Different GS monomers play different roles of anti-hepatoma through their respective channels.
