Analysis on the value of three indicators in diagnosis for acute pulmonary embolism
10.3969/j.issn.1673-4130.2015.22.020
- VernacularTitle:3项指标在急性肺栓塞患者临床诊断中的价值分析
- Author:
Minghua ZHANG
;
Mingming SHUI
;
Jun YAO
;
Bicui LIU
- Publication Type:Journal Article
- Keywords:
plasma troponin;
B-type natriuretic peptide;
D-dimer;
acute pulmonary embolism
- From:
International Journal of Laboratory Medicine
2015;(22):3271-3272
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of plasma troponin ,B-type natriuretic peptide and D-dimer in the clinical diagnosis of acute pulmonary embolism .Methods A total of 116 patients with acute pulmonary embolism were randomly selected and divided into high-risk group and low-risk group according to the patient′s condition ,58 patients in each group .Enzyme-linked immunosor-bent assay was used to detected levels of plasma troponin ,B-type natriuretic peptide and D-dimer .Results The plasma troponin and B-type natriuretic peptide levels in the high-risk group were significant higher than those of the low-risk group(P<0 .05) ,but there was no significant difference on D-dimer level(P>0 .05) .The positive rate of plasma troponin(61 .21% )and B-type natriuretic pep-tide(74 .14% )were significant higher than that of D-dimer(36 .21% ) ,the differences were significant(P<0 .05) .The sensitivity of D-dimer was 81 .4 % ,specificity was 86 .7% .The sensitivity of plasma troponin was 95 .6% ,the specificity was 86 .7% .The sensi-tivity of B-type natriuretic peptide was 97 .1% ,the specificity was 95 .9% .The sensitivity and specificity of plasma troponin and B-type natriuretic peptide were significant higher than D-dimer(P<0 .05) .Conclusion Plasma troponin ,B-type natriuretic peptide and D-dimer have certain implications for the clinical diagnosis of acute pulmonary embolism ,but plasma troponin ,B-type natriuretic peptide has better sensitivity and specificity compared with D-dimer .
