Correlation of serum hs-CRP and IL-6 levels with cerebral hemorrhage volume and nerve function damage
10.3969/j.issn.1009-0126.2015.11.014
- VernacularTitle:血清高敏C反应蛋白和白细胞介素6水平与脑出血量及神经功能损伤的相关性
- Author:
Xiaodong LIAN
;
Qi LIN
- Publication Type:Journal Article
- Keywords:
C-reactive protein;
interleukin-6;
cerebral hemorrhage;
cranial nerve injuries
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2015;(11):1175-1177
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlation of serum hs‐CRP and IL‐6 levels with cerebral hemorrhage volume and nerve function damage .Methods One hundred and two cerebral hemor‐rhage patients served as an experimental group and 64 individuals undergoing physical examina‐tion served as a control group in this study .The patients in experimental group were further di‐vided into mild damage group (n= 29) ,moderate damage group (n= 42) ,severe damage group (n=31) ,10 ml hemorrhage group(n=15) ,10 -30 ml hemorrhage group (n=52) ,and >30 ml hemorrhage group (n=35) .Their serum hs‐CRP and IL‐6 levels were measured on days 1 ,5 ,10 and 15 after admission .Results The serum hs‐CRP and IL‐6 levels in experimental group in‐creased gradually in the first 5 days ,reached their peak on day 5 and then decreased gradually (P<0 .05) .The serum hs‐CRP and IL‐6 levels were significantly higher in severe damage group than in mild and moderate damage groups ( P<0 .05) ,and in experimental group than in control group (9 .46 ± 1 .26 mg/L vs 4 .24 ± 0 .94 mg/L ,P=0 .02) .Conclusion The serum hs‐CRP and IL‐6 levels are related with cerebral hemorrhage volume and nerve function damage ,and can thus be considered as an important parameter in clinical testing .
