Risk factors of suicidal attempt in major depressive disorder patients with anxious characteristics
10.3969/j.issn.1002-0152.2015.10.007
- VernacularTitle:伴焦虑症状抑郁症患者自杀未遂的危险因素
- Author:
Limin XIN
;
Lin CHEN
;
Fude YANG
;
Suoyuan ZHANG
;
Jun WANG
;
Gang WANG
;
Yiru FANG
;
Zheng LU
;
Haichen YANG
;
Jian HU
;
Zhiyu CHEN
;
Yi HUANG
;
Jing SUN
;
Xiaoping WANG
;
Huichun LI
;
Jinbei ZHANG
;
Tianmei SI
- Publication Type:Journal Article
- Keywords:
Depressive disorder;
Anxious;
Suicide attempt;
Risk factor
- From:
Chinese Journal of Nervous and Mental Diseases
2015;(10):613-617
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of socio-demographic and clinical characteristics related to sui?cidal attempt in major depressive disorder (MDD) patients with anxious characteristics. Methods Based on the anxious module of Mini International Neuropsychiatric Interview (MINI), a total of 728 anxious MDD patients from 13 major men?tal health centers in China were classified as suicidal and non-suicidal attempt groups. Further analyses regarding risk factors of suicidal attempt in anxious MDD patients were performed by the multivariate logistic regression analysis. Re?sults Among the 728 patients with anxious MDD analyzed, 135 (18.5%) of them had suicidal attempt and 593 (81.5%) had non-suicidal attempt. Compared to the non-suicidal attempt group, patients with suicidal attempt had significantly earlier age onset[(32.3 ± 11.9) vs. (35.3 ± 13.1)], more lifetime depression episodes (median:2 vs. 2), more number of ad?missions (median: 1 vs. 0), more frequent depressive episodes (14.8% vs. 7.4%), more atypical characteristics (25.9%vs.15.0%), more suicidal ideation (78.5%vs. 50.3%) and more antidepressant use (81.5%vs. 71.2%). Logistic regression analysis showed that number of admissions (OR=1.18, 95%CI:1.02~1.37), frequent depressive episodes (OR=2.10, 95%CI:1.14~3.68), depressive episodes with suicidal ideation (OR=3.55, 95%CI:2.28~5.54) were associated with suicidal at?tempt in MDD patients with anxious characteristics (P<0.05). Conclusions More number of admissions, more frequent depressive episodes, comorbid suicidal ideation may be risk factors of suicidal attempt in anxious MDD patients.
