Denervation of the inferior alveolar nerve is associated with bone formation and bone mass maintenance in extraction sockets
10.3969/j.issn.2095-4344.2015.42.004
- VernacularTitle:失下牙槽神经支配与拔牙窝新骨形成及骨量保持
- Author:
Chengyong WANG
;
Weihui CHEN
;
Meng LU
;
Jin WANG
;
Chuanqing MAO
;
Hai LIN
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2015;(42):6740-6745
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: There is a close relationship between innervations and bone formation and bone mass maintenance in the extraction sockets. OBJECTIVE:To study the possible effect of denervations on the regulation of new bone formation and bone mass maintenance in the extraction sockets. METHODS:The unilateral inferior nerve of dogs was sectioned to establish an animal denervation model. The normal side was used as control. After model establishment, the premolars of denervated side and normal side were extracted. Histological method was used to test new bone formation and bone mass maintenance in the extraction sockets at the 2nd, 4th, 8th and 12th weeks after tooth extraction. RESULTS AND CONCLUSION:The percentage of new bone areas in the extraction sockets was significantly lower in the experiment group than the control group at weeks 2, 4, 8 after tooth extraction (P < 0.01). The height difference between the buccal and lingual alveolar ridge was higher in the experimental group than the control group at weeks 2, 4, 8, 12 after tooth extraction (P < 0.05 or P < 0.01). These findings indicate that denervation is closely related with new bone formation and bone mass maintenance in the extraction sockets.
