Related Risk Factor Analysis for Ventricular Aneurysm Formation in Patients After Acute Myocardial Infarction
10.3969/j.issn.1000-3614.2015.10.006
- VernacularTitle:急性心肌梗死后室壁瘤形成的相关因素分析
- Author:
Ming BAI
;
Jun PANG
;
Hanxiang GAO
;
Aiyun DENG
;
Qiang LI
;
Yu PENG
;
Hong KANG
;
Tao WANG
;
Changyuan CHEN
;
Dong WANG
;
Bo ZHANG
;
Shijie WANG
;
Suyu YAO
;
Zheng ZHANG
- Publication Type:Journal Article
- Keywords:
Acute myocardial infarction;
Ventricular aneurysm;
Risk factor
- From:
Chinese Circulation Journal
2015;(10):950-953
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the risk factors for ventricular aneurysm formation in patients after acute myocardial infarction (AMI).
Methods: Our research included 2 groups of AMI patients who received percutaneous coronary intervention (PCI)
in our hospital from 2012-04 to 2014-07 as Ventricular aneurysm group,n=146 and Control group,n=142, in which the AMI patients without ventricular aneurysm formation. The baseline condition with aneurysm related risk factors were analyzed and compared between 2 groups including age, gender, hypertension, hyperlipidaemia, diabetes, smoking, family history, MI history, anterior myocardial wall infarction, angina pectoris, left main (LM) disease, the lesion at proximal left anterior descending (LAD) artery, NYHA classiifcation III/IV, chest pain time ≥ 24 hours and ST-segment elevation ≥ 4 adjacent leads in ECG.
Results: Compared with Control group, the patients in Ventricular aneurysm group had the elder age (OR=1.023, 95% CI 1.000-1.046), higher incidence rates of smoking (OR=1.819, 95% CI 1.130-2.928) and anterior MI (OR=9.162, 95% CI 4.657-18.028), more patients with ≥ 4 adjacent ST-segment elevation (OR=6.571, 95% CI 2.426-17.798), while less patients with angina pectoris (OR=0.557, 95% CI 0.335-0.927, allP<0.05. With adjusted relating factors of age, gender, hypertension, diabetes and angina pectoris, the multivariate Logistic regression analysis indicated that smoking (regression coefifcient: 0.833, OR=2.301, 95% CI 1.283-4.125), anterior MI (regression coefifcient: 1.799, OR=6.041, 95% CI 2.831-12.894) were positively related to ventricular aneurysm formation.
Conclusion: Smoking and anterior MI were strongly related to ventricular aneurysm formation in patients after AMI.
