Clinical Features of Ocular Toxoplasmosis in Korean Patients.
10.3347/kjp.2011.49.2.167
- Author:
Young Hoon PARK
1
;
Jae Hyung HAN
;
Ho Woo NAM
Author Information
1. Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea.
- Publication Type:Case Report
- Keywords:
Toxoplasma gondii;
toxoplasmosis;
retinochoroiditis;
funduscopy;
IgG-ELISA
- MeSH:
Adrenal Cortex Hormones/administration & dosage;
Adult;
Age Distribution;
Aged;
Anti-Inflammatory Agents/administration & dosage;
Antibodies, Protozoan/*blood;
Antiprotozoal Agents/administration & dosage;
Cataract/pathology;
Enzyme-Linked Immunosorbent Assay;
Female;
Humans;
Immunoglobulin G/blood;
Korea;
Male;
Middle Aged;
Optic Atrophy/pathology;
Retinal Neovascularization/pathology;
Sex Distribution;
Toxoplasma/immunology/*isolation & purification;
Toxoplasmosis, Ocular/complications/*diagnosis/drug therapy/*pathology;
Uveitis, Anterior/complications/drug therapy/parasitology/pathology
- From:The Korean Journal of Parasitology
2011;49(2):167-171
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report here the records of 10 consecutive Korean patients (10 eyes) with ocular toxoplasmosis which showed the typical clinical manifestations with seropositivity for Toxoplasma gondii specific IgG antibodies by micro-ELISA between 2006 and 2010. Nine patients were males and 1 was female; their age was 50.5+/-13.8 years. The most common accompanying signs were vitritis (100%), anterior uveitis (70%), and scattered white deposit (80%). Pre-existing retinochoroidal scar was found in 1 (10%) patient. All patients received antiparasitic chemotherapy and systemic corticosteroid treatment, which resolved the presenting attack and recovered the visual acuity better than initial one in 9 patients and worse in 1. Optic atrophy, cataract, and retinal neovascularization were observed during the follow-up period and recurrence was detected in 3 eyes (30%) 6 to 20 months after the initial attack. In Korea, although rarely detected and reported, ocular toxoplasmosis needs more attention in clinical field of retinal diseases.
