Research progress of animal models of systemic lupus erythematosus
10.3969/j.issn.1005-4847.2015.04.019
- VernacularTitle:系统性红斑狼疮动物模型研究进展
- Author:
Yu YAN
;
Lianhua FANG
;
Guanhua DU
- Publication Type:Journal Article
- Keywords:
Systemic lupus erythematosus;
Murine;
Animal models
- From:
Acta Laboratorium Animalis Scientia Sinica
2015;(4):428-433
- CountryChina
- Language:Chinese
-
Abstract:
Systemic lupus erythematosus ( SLE) is a chronic multisystem relapsing-remitting autoimmune disease, which affects human health seriously.There are numerous animal models that have long been employed in an effort to un-derstand the mechanism and treatment of SLE.Animal models of SLE were reviewed and compared in this paper, to provide references for the researchers to choose appropriate models for studying specific pathogenic mechanism and diagnostic crite-ria, searching for targeted treatment interventions and developing potential therapeutic drugs.
