Review of the application of neonatal maternal separation model in irritable bowel syndrome (IBS) studies
10.3969/j.issn.1005-4847.2015.04.020
- VernacularTitle:肠易激综合征母婴分离模型应用进展
- Author:
Zesi LIN
;
Hongqi WANG
- Publication Type:Journal Article
- Keywords:
Neonatal maternal separation;
Animal model;
Irritable bowel syndrome,IBS
- From:
Acta Laboratorium Animalis Scientia Sinica
2015;(4):434-439
- CountryChina
- Language:Chinese
-
Abstract:
The neonatal maternal separation ( NMS) model has been ubiquitously used in studies of irritable bowel syndrome ( IBS) ,which mimics the disease characterized by visceral hypersensitivity, and GI dismotility and mental disor-der.This minireview focuses on the features and certain pathological mechanism of the animal models.