Analysis of Four Effective Components in Jinhoujian Spray by Quantitative Analysis of Multi-components by Single Marker
10.3870/j.issn.1004-0781.2015.10.025
- VernacularTitle:一测多评法同时测定金喉健喷雾剂中4种有效成分?
- Author:
Liou WANG
;
Juanyan YANG
;
Xiangjun MAO
;
Weiwei YANG
;
Yi LUO
- Publication Type:Journal Article
- Keywords:
Jinhoujian spray;
Quantitative analysis of multi-components with a single-marker;
Correlation factors,relative;
Content determination
- From:
Herald of Medicine
2015;(10):1356-1360
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a methodological study pattern of quantitative analysis of multi-components by single marker ( QAMS) , and examine its feasibility and technical applicability in the quality control of compound preparation of traditional Chinese medicine-Jinhoujian spray. Methods Gas chromatographic method ( GC) was used and naphthalene served as the internal standard. Menthol was used as the reference substance. The relative correlation factors ( RCF) of 1,8-Cineole, camphor and borneol to menthol were calculated and established to carry out QAMS.The accuracy of this method was confirmed by comparison of internal standard method. Results The reproducibility of relative correction factor was perfect. The two methods did not show significant difference in 10 bathes of samples. Conclusion The QAMS method is feasible, credible, and can be used to determine active ingredients in Jinhoujian spray.
