Application of diffusion tensor tractography in grading gliomas

VernacularTitle:扩散张量纤维束成像在脑胶质瘤分级中的应用
Author: Xinhua XU ; Guiquan SHEN ; Jin ZHANG ; Xudong SHEN ; Yingjun ZHANG
Publication Type:Journal Article
Keywords: glioma; magnetic resonance imaging; diffusion tensor tractography; fiber density index
From: Journal of Practical Radiology 2015;(9):1424-1427
CountryChina
Language:Chinese
Abstract: Objective To explore the value of diffusion tensor tractography (DTT)in grading gliomas.Methods 27 patients with brain glioma(gradeⅠ-Ⅱ in 1 1 cases and grade Ⅲ-Ⅳ in 1 6 cases)confirmed by pathology were collected.Conventional MR and DTT were carried out and the bilateral corticospinal tracts(CST)were reconstructed before operation.The fiber density index (FDi)and relative FDi (rFDi= ipsilateral FDi/contralateral FDi)of CST was measured.Results The FDi of ipsilateral CST was lower than that of the contralateral CST in all patients(P <0.05).The bilateral FDi had no statistical difference in low-grade glioma (LGG)and high-grade glioma (HGG)(P >0.05).The rFDi of LGG was higher than that of HGG (P <0.05).Conclusion In com-bination with conventional MR,DTT can improve the accuracy of grading gliomas.