Minimal inhibitory concentration (M.I.C) of antibiotics to S.typhi strains isolated at Daklak from 1996-1998
- Author:
Nguyen Ngoc Hung
- Publication Type:Journal Article
- Keywords:
S.typhi
- MeSH:
Anti-Bacterial Agents;
drugs;
Salmonella typhi
- From:Journal of Medical Research
2003;23(3):28-32
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
For the first time in Daklak, S. typhi strains were isolated from cases of suspected typhoid fever. MIC was investigated on 50 strains of S. typhi in Daklak from 1996-1998. The results were as following:
All these isolated S.typhi strains were fully sensitive to common antibiotics (1g/ml for Tetracycline, Trimethoprim/sulfamethoxazole and 4 g/ml for Ampicillin, Nalidixic acid and the third generation cephalosporin (Ceftriaxone M.I.C=0.125 g/ml) and the fluoquinolones (Ofloxacin M.I.C =0.25 g/ml), especially to 16% of Chloramphenicol-resistant isolates (with M.I.C = 64 g/ml). This is a great difference to compare with S.typhi strains isolated in Northern and Southern in Vietnam.
Concerning the plasmid profile analysis, from 50 strains of S.typhi, the results showed that:
All these strains did not harbour any R-plasmid.
43 strains harboured a plasmid lower than 70 Md.
7 strains did not harbour any kind of plasmids.
